If I have the time to do it I will use Tear Mender to place the patch and seal its edges then run a quick lock stitch around the perimeter of the patch. But in my opinion, it is not really necessary. I have numerous pairs of pants, as well as shirts, that have nothing but tear mender applied patches. They survived countless washes as well as a really tough work environment. The greatest thing about tear mender is its on the spot repair qualities. This on the go quality makes it easy to prevent small tears from becoming big holes, and even bigger problems. How many of us out there have had a small tear on a trip turn a perfectly good bag or pair of coveralls into a shredded mass of cloth, sand, and mud. This type of equipment failure can turn a pleasant trip, into a miserable, sodden, exhausting, expedition, or possibly cause you and your friends to abort a long anticipated and planned for trip.
With Tear Mender you can stop the hole as soon as it starts thus averting disaster. And because Tear Mender is 100% latex it remains flexible in any temperature and will not cause clothing to stiffen noticeably. You do not need to coat the entire surface under the patch only about 1/4 to 1/2" in, around the outer perimeter of the patch. This will allow the patch to retain maximum flexibility and still stick like.. ( well.... Glue!!).
And as a side note I am in no way associated with Tear Mender or its affiliates.... This is a recommendation based on my experiences and those who have come before me.